UVA.edu Department of Kinesiology · School of Education and Human Development
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TEMPO@UVA
Translational Exercise and Mitochondrial Performance Optimization Laboratory
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Publications

Selected peer-reviewed publications and preprints. The full citation list is set out below, newest first; PubMed indexes the same record under the author search “Irving BA.”

95+
Peer-reviewed publications
122+
Presentations
23
Invited talks
37
Funded grants & contracts
Google Scholar ORCID Full CV (PDF)

Dr. Irving's name is set in bold in each citation. A "#" denotes corresponding authorship.

2026

6 papers
96

Near infrared spectroscopy-derived muscle oxidative capacity correlates to oxidative metabolic predictors of performance in highly trained female middle-distance runners. 

Schoeberlein MI, Hunter LD, Richardson EW, Irving BA, Wilkins BW. 

Physiol Rep. 2026 Aug;14(15):e71047. PMID: 42572413; PMCID: PMC13454737.
95

A Peripheral Perspective on Brain Health: Vascular and Skeletal Muscle Contributions.

Keller JL, Pennartz KJ, Sprick JD, Hein EJ, Irving BA, Vann CG, Butlig ER, Al-Masri S, Nelson AR.

Am J Physiol Heart Circ Physiol. 2026 Aug 7. doi: 10.1152/ajpheart.00462.2026. Epub ahead of print. PMID: 42565788.
94

Impact of Prior Bariatric Surgery Versus Immediate Total Knee Arthroplasty on Knee Function Among Patients Who Have Severe Obesity and Advanced Knee Osteoarthritis: The SWIFT Trial.

Benotti PN, Wood GC, Irving BA, Ricciardi BF, Schwarzkopf R, Parikh MS, Browne JA, Seiler JL, Samuels J, Still CD; SWIFT Writing Committee.

J Arthroplasty · 2026 May 24 · PMID 42184930
93

Low-dose simulated galactic cosmic radiation exposure after hindlimb unloading has long-term impact on skeletal muscle metabolic proteins in female mice.

Martone M, Irving BA, Spielmann G, Johannsen NM, Robinson MM, Chancellor JC, Allaway HCM.

Am J Physiol Regul Integr Comp Physiol · 2026 Jun 1;330(6):R582-R589 · PMID 42059871
92

Characterizing Biomarkers of Muscle Damage in Collegiate Football Players: A Prospective, Repeated Measures Study.

Brandhurst G, Piedy E, Etheredge S, Martone M, Quiriarte HD, Phillips P 4th, Calvert D, Lemoine NP Jr, Marucci J, Irving BA, Zura R, Spielmann G, Johannsen NM, Matthews R.

J Clin Med · 2026 Mar 25;15(7):2502 · PMID 41976803
91

The association between radiographic osteosarcopenia and overall mortality among older patients undergoing colorectal cancer resection.

Papadopoulos E, Irving BA, Allaway HCM, Spielmann G, Lin M, Finan KR.

Aging Clin Exp Res · 2026 · doi: 10.1007/s40520-026-03372-w

2025

6 papers
90

The Contribution of Tissue-Specific Mitochondrial Respiration to Individual Variation in Oxygen Uptake during Rest and Exercise by the Gulf Killifish, Fundulus grandis.

Brieske SD, Irving BA, Rees BB.

Ecol Evol Physiol · 2025 Jul-Aug;98(4):244-259 · PMID 41105886
89

Sarcopenia and Cachexia in Older Patients with Cancer: Pathophysiology, Diagnosis, Impact on Outcomes, and Management Strategies.

Papadopoulos E, Irving BA, Brown JC, Heymsfield SB, Sattar S, Alibhai SMH, Williams GR, Dunne RF.

Drugs Aging · 2025 Oct 8 · PMID 41060616
88

Reliability and Inter-Device Agreement Between a Portable Handheld Ultrasound Scanner and a Conventional Ultrasound System for Assessing the Thickness of the Rectus Femoris and Vastus Intermedius.

Emerson C, Kim HK, Irving BA, Papadopoulos E.

J Funct Morphol Kinesiol · 2025 Aug 1;10(3):299 · PMID 40843830
87

Effects of lactate concentration on T-cell phenotype and mitochondrial respiration.

Cho E, Spielmann G, Irving BA#.

Physiol Rep · 2025 Jul;13(14):e70450 · PMID 40705846Corresponding
86

Effect of training status on muscle excitation and neuromuscular fatigue with resistance exercise with and without blood flow restriction in young men.

Davis BH, Spielmann G, Johannsen NM, Fairchild V, Allerton TD, Irving BA#.

Physiol Rep · 2025 Mar;13(6):e70274 · PMID 40110914Corresponding
85

Impact of Voluntary Exercise on Systemic Inflammation in a 2-Hit Model of Heart Failure With Preserved Ejection Fraction.

Quiriarte H, Cho E, Kim Y, Doiron JE, Davis G, Stampley J, Noland RC, Li Z, Shah SJ, Irving BA, Spielmann G, Lefer DJ, Allerton TD.

J Am Heart Assoc · 2025 Mar 4;14(5):e10753 · PMID 40028883

2024

5 papers
84

Exercise Therapy Rescues Skeletal Muscle Dysfunction and Exercise Intolerance in Cardiometabolic HFpEF.

Quiriarte H, Noland RC, Stampley JE, Davis G, Li Z, Cho E, Kim Y, Doiron J, Spielmann G, Ghosh S, Shah SJ, Irving BA, Lefer DJ, Allerton TD.

JACC: Basic to Translational Science · 2024;9(12):1409-25
83

Nitric oxide donors rescue metabolic and mitochondrial dysfunction in obese Alzheimer's model.

Allerton TD, Stampley JE, Li Z, Yu X, Quiariate H, Doiron JE, White G, Wigger Z, Gartia MR, Lefer DJ, Soto P, Irving BA.

Sci Rep · 2024 Oct 30;14(1):26118 · PMID 39478095
82

Impact of low-load resistance exercise with and without blood flow restriction on muscle strength, endurance, and oxidative capacity: A pilot study.

Davis BH, Stampley JE, Granger J, Scott MC, Allerton TD, Johannsen NM, Spielmann G, Irving BA#.

Physiol Rep · 2024 Jun;12(12):e16041 · PMID 38888154Corresponding
81

Commentary: Unraveling the Roles of Ectopic Adipose Depots and Physical Activity in Age-related Mitochondrial Decline.

Irving BA and Kunz HE.

Obesity (Silver Spring) · 2024 Jun;32(6):1043-1044 · PMID 38803313
80

A single exposure to 100% normobaric oxygen therapy appears to improve sequence learning processes by increasing prefrontal cortex oxygen saturation.

Wang Z, Irving BA, Spielmann G, Johannsen N, Greenway F, Dalecki M.

Brain Res · 2024 Aug 15;1837:148962 · PMID 38670479

Selected earlier work

Career highlights
32

A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy.

Ruas JL, White JP, Rao RR, Kleiner S, Brannan KT, Harrison BC, Greene NP, Wu J, Estall JL, Irving BA, Lanza IR, Rasbach KA, Okutsu M, Nair KS, Yan Z, Leinwand LA, Spiegelman BM.

Cell · 2012 Dec 7;151(6):1319-31 · PMID 23217713
42

Combined training enhances skeletal muscle mitochondrial oxidative capacity independent of age.

Irving BA#, Lanza IR, Henderson GC, Rao RR, Spiegelman BM, Nair KS.

J Clin Endocrinol Metab · 2015;100(4):1654-63Corresponding
43

Mechanism by Which Caloric Restriction Improves Insulin Sensitivity in Sedentary Obese Adults.

Johnson ML, Distelmaier K, Lanza IR, Irving BA, Robinson MM, Konopka AR, Shulman GI, Nair KS.

Diabetes · 2016;65(1):74-84
41

Defects in mitochondrial efficiency and H₂O₂ emissions in obese women are restored to a lean phenotype with aerobic exercise training.

Konopka AR, Asante A, Lanza IR, Robinson MM, Johnson ML, Dalla Man C, Cobelli C, Amols MH, Irving BA, Nair KS.

Diabetes · 2015;64(6):2104-15
22

Age, obesity, and sex effects on insulin sensitivity and skeletal muscle mitochondrial function.

Karakelides H, Irving BA, Short KR, O'Brien P, Nair KS.

Diabetes · 2010;59(1):89-97
10

Effect of exercise training intensity on abdominal visceral fat and body composition.

Irving BA, Davis CK, Brock DW, Weltman JY, Swift D, Barrett EJ, Gaesser GA, Weltman A.

Med Sci Sports Exerc · 2008;40(11):1863-72

Book chapters

Systems Immunity and Exercise.

Kunz HE, Irving BA, Karl JP, Quiriarte H.

Exercise Immunology (2nd ed.) · Turner J, Spielmann G, Campbell J, eds. · 2024

Preprints

Resolving the Rotenone Paradox: elucidating the complexity of multi-substrate respirometry protocols.

Chicco AJ, Zilhaver PT, Whitcomb LA, Fresa KJ, Izon CS, Gonzalez Franquesa A, Dometita C, Irving BA, Garcia-Roves PM.

MitoFit Preprints · 2022.17 · doi: 10.26124/mitofit:2022-0017

Mitochondrial respiratory states and rates: Building blocks of mitochondrial physiology.

Gnaiger E (corresponding); MitoEAGLE consortium (incl. Irving BA).

MitoEAGLE preprint · 2018-06-10(39)
Mitochondrial physiology, measured cleanly and repeatedly.
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Department of Kinesiology
University of Virginia · Charlottesville, VA
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